Perbandingan Efektivitas Kombinasi Ekstrak Jahe dan Piridoksin dengan Piridoksin Saja dalam Mengurangi Keluhan Mual Muntah pada Wanita Hamil

Rimonta F. Gunanegara, Syafriani Tanjung, Aloysius Suryawan, Ucke S. Sastrawinata


Nausea and vomiting are the most common symptoms in pregnancy and have affected 50-80% pregnant women. Ginger extract (Zingiber Officinale Roscoe) has been known as a traditional anti nausea medication for a long time. This study aims to compare the efficacy of ginger extract-pyridoxine medication and the pyridoxine only medication for decreasing nausea and vomiting symptoms in women with under 3 months’ pregnancy. A randomized controlled prospective study was conducted to 70 pregnant women with less than 10 gestasional weeks who had attended the antenatal care in Immanuel Hospital, Bandung. The study group obtained 350 mg ginger extract + 3.5 mg pyridoxine 2 times a day while the control group obtained 25 mg pyridoxine 3 times a day for 7 days. Nausea and vomiting symptoms were measured using 3 scales (Rhodes Index, Likert Scale, and Visual Analog Scale) from day 1 to 7. Ginger extract-pyridoxine combination showed a better result with minimized nausea and vomiting symptoms, than pyridoxine-only. The nausea and vomiting symptoms scale used in the study showed statistically significant difference (p<0.001).


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